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Endogenous Opioid Mechanisms for Rejection Sensitivity

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“Endogenous Opioid Mechanisms for Rejection Sensitivity”

This project hypothesizes that the brain's opioid system determines rejection sensitivity, a personality trait that is a vulnerability factor and feature of several psychiatric disorders. This project will use positron emission tomography to measure the brain's opioid response to social rejection and acceptance in a nonclinical population with varying levels of rejection sensitivity. The results will provide the first major step towards understanding a neurotransmitter mechanism for rejection sensitivity, allowing for further investigation into predicting and treating its associated disorders.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

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Endogenous Opioid Mechanisms for Rejection Sensitivity

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NCT02189785

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0dN8Ka