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Mental Health, Vascular Function, and Exercise Tolerance

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Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

Specific Aim #1: Examining the impact of mental health disorders (PTSD and GAD) on peripheral vascular function and sympathetic nervous system activity in young individuals. Specific Aim #2: Examining the impact of mental health disorders (PTSD and GAD) on peripheral hemodynamics and metabolic byproducts during small muscle mass exercise in young individuals. Specific Aim #3: Examining the impact of mental health disorders (PTSD and GAD) on exercise tolerance, peripheral hemodynamics and metabolic byproducts during large muscle mass exercise in young individuals.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Dietary Supplement - PTSD/GAD Antioxidant

Subjects will ingest an antioxidant cocktail containing 800 milligrams of alpha lipoic acid, 1 gram of vitamin C (ascorbic acid), and 400 milligrams of vitamin E (alpha tocopherol).

Dietary Supplement - PTSD/GAD Placebo

Subjects will ingest placebo (microcrystalline cellulose) pills.

Dietary Supplement - Healthy Control Antioxidant

Subjects will ingest an antioxidant cocktail containing 800 milligrams of alpha lipoic acid, 1 gram of vitamin C (ascorbic acid), and 400 milligrams of vitamin E (alpha tocopherol).

Dietary Supplement - Healthy Control Placebo

Subjects will ingest placebo (microcrystalline cellulose) pills.

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Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

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NCT03216980

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0dNgze