Effect of Heavy Alcohol Consumption on Liver Function
common.study.values.description
“Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling”
The main purpose of this study is to see whether heavy drinking will interfere with a specific pathway, called FXR signaling in the liver. The abnormality of this pathway may lead to liver injury in some patients who drink heavily.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Placebo
1 tablet of placebo, taken orally daily with water, approximately 30 minutes prior to breakfast for 4 weeks.
Drug - 10 mg Obeticholic Acid (OCA)
10 mg Obeticholic Acid (OCA) Study medication will be administered orally, once daily, approximately 30 minutes prior to breakfast for 4 weeks.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
common.study.values.clinical-trial-id
NCT02654236
participant.views.study.view.id
1aK98d
