“Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)”
This will be a prospective study examining the use of 99mTc-Annexin V-128 (AxV-128/Tc) single-photon emission computed tomography (SPECT)/computerized tomography (CT) technology in the imaging and functional assessment of the lung of patients with chronic obstructive pulmonary disease (COPD), healthy volunteer smokers without COPD and healthy volunteer subjects without smoking history. The aim of study is to determine if patients with COPD have an increased AxV-128/Tc signal with SPECT/CT.
Radiation - SPECT-CT imaging
Injection of AxV-128 labeled with 99mTc followed by SPECT-CT
Drug - AxV-128/Tc
Injection of AxV-128 labeled with 99mTc
In Vivo Imaging of Destructive Processes in Chronic Obstructive Pulmonary Disease (COPD)