Effect of Statin Use on Aldosterone Secretion
common.study.values.description
“Effect of Statin Use on Aldosterone Secretion”
The purpose of this research protocol is to determine if the same effects are observed in vivo in humans through a randomized controlled study. Data regarding a novel mechanism of the widely used statin class of medications on the mineralocorticoid pathway would likely have significant clinical implications on the future management of hypertension and other cardiovascular disease given the known pleiotropy of aldosterone action.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Placebo
Placebo prepared by Investigation Drug Services at Brigham and Women's Hospital
Drug - Simvastatin
Simvastatin 40 mg daily
Drug - Pravastatin
Pravastatin 80 mg daily
participant.views.study.view.additional
participant.views.study.view.scientific-title
Effect of Statin Use on Aldosterone Secretion
common.study.values.clinical-trial-id
NCT02871687
participant.views.study.view.id
7ax5Bb
