common.study.topics.clinical

Dose Response of Epinephrine

common.study.values.description

Dose Response of Epinephrine

Epinephrine is the principal physiologic defense against hypoglycemia in type 1 and longer duration type 2 DM. Despite this, it is unknown how epinephrine regulates in-vivo endothelial function and atherothrombotic balance in humans. The specific aim of our study will be to determine the dose response effects of the key ANS counterregulatory hormone epinephrine on endothelial function, fibrinolytic balance and pro-atherogenic inflammatory mechanisms in healthy humans.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Epinephrine

Dose response of epinephrine infusion

Saline infusion

Placebo

participant.views.study.view.additional

participant.views.study.view.scientific-title

Hypoglycemia Associated Autonomic Dysfunction Dose Response of Epinephrine

common.study.values.clinical-trial-id

NCT02692313

participant.views.study.view.id

7axLPa