common.study.topics.clinical

Personalized Dosing of Nicotine Replacement (NRT to Effect)

common.study.values.description

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Medications for smoking cessation are currently only effective in helping a minority of smokers quit. Drug development is slow and expensive, so there is much interest in optimizing the effectiveness of existing treatments and medications. Current standard doses of nicotine replacement therapy (NRT) are not effective for many smokers and in many cases provide less nicotine compared to when a smoker is smoking their usual number of cigarettes. The proposed study will test if a personalized dose of nicotine patch (up to 84mg) will improve quitting success in those who do not respond to a standard dose of NRT (21mg).

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Recruiting patients only common.study.methods.is-healthy-yes

Drug - Nicotine Patch

Active nicotine patch of 21 mg, 14 mg and 7 mg

Drug - Placebos

Matching placebo patches of 21 mg, 14 mg and 7 mg

participant.views.study.view.additional

participant.views.study.view.scientific-title

Personalized Dosing of Nicotine Replacement for Smoking Cessation: An Effectiveness Randomized Placebo-controlled Trial

common.study.values.clinical-trial-id

NCT03000387

participant.views.study.view.id

7axm3b