Confocal Endomicroscopy for Non-Erosive Reflux Disease
common.study.values.description
“Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection”
Primary Objective: Evaluate response to NERD treatment between patients with normal endomicroscopy findings compared with patients with abnormal endomicroscopy findings. Secondary Objectives: To evaluate the role of probe based endomicroscopy in the diagnosis of NERD by evaluating dilated intercellular spaces, evaluation of IPCL, and quantification of fluorescein leak. Quality of life at study entry and end of study. Compare two medications under study within each group as a subgroup analysis.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Proton Pump Inhibitor (PPI) Therapy
Subject will take a proton pump inhibitor (PPI) of their choice (Omeprazole, Esomeprazole, Pantoprazole, or Lansoprazole) 2 times a day for 8 weeks.
Drug - Sucralfate
Subject will take Sucralfate 4 times a day for 8 weeks.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection (CENERDD)
common.study.values.clinical-trial-id
NCT02788591
participant.views.study.view.id
7e5wYb
