common.study.topics.clinical

THC, Cannabis, and Psychosis

common.study.values.description

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone: Sub-Study I

The overall purpose of this study is to examine the effect of Pregnenolone (PREG) on the acute psychosis-like and cognitive effects of Delta-9-Tetrahydrocannabinol (THC). This will be tested by pretreating healthy individuals with PREG, and then assessing their responses to Dronabinol (THC).

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Active Dronabinol

20 mg capsule of Dronabinol will be administered orally

Drug - Active Pregnenolone

1.79 mg/kg of Pregnenolone will be administered sublingually (under the tongue)

Drug - Placebo Dronabinol

Control: Placebo pill (no active cannabinoids) administered orally

Drug - Placebo Pregnenolone

Control: Placebo given sublingually (under the tongue)

participant.views.study.view.additional

participant.views.study.view.scientific-title

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone: Sub-Study I

common.study.values.clinical-trial-id

NCT02811939

participant.views.study.view.id

9aAr9b