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Cannabis Smoking, Oxidative Stress and Lung Immune Response

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Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Procedure - Bronchoscopy

Passage of a thin flexible tube through the mouth, into the windpipe and then into the bronchial tubes so that the study doctor can look into the lungs to perform Bronchoalveolar lavage (BAL), cytologic brushing, and protected specimen brushing.

Radiation - Chest X-ray

To identify any previously undiagnosed lung disease that will either increase the risk of bronchoscopy or confound results of the study.

Procedure - Venipuncture

To collect blood cells and serum for analyses.

Procedure - Intravenous Catheter

To administer the appropriate medications for the bronchoscopy procedure.

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Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

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NCT02480283

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9av9Me