Effects of Aging and Exercise
“Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise”
Advanced age is the main risk factor for chronic diseases such as cardiovascular disease, type 2 diabetes, Alzheimer's disease and cancer. One reason may be due to decreased resistance to oxidative stress as antioxidant defenses and cell protection is reduced with aging. This has been shown in animal studies and also that the impairment can be somewhat restored with exercise. This will be the first study to test this in humans by comparing young and older inactive adults before and after an exercise intervention, a practical and cost-effective intervention that can have tremendous public health impact by lowering risk for disease and medical-related costs.
Behavioral - Exercise Intervention
24 sessions of aerobic exercise
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise