Treatment of High Blood Pressure

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

The purpose of the study is to show the blood pressure lowering effect of aprocitentan, a new drug, when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure (hypertension), and to show that blood pressure reduction is kept for long period of time.

Pharmaceutical medication involved
Recruiting patients only

Drug - Aprocitentan 12.5 mg

Tablet, oral use

Drug - Aprocitentan 25 mg

Tablet, oral use

Drug - Placebo

Matching placebo tablet

Multi-center, Blinded, Randomized, Parallel-group, Phase 3 Study With Aprocitentan in Subjects With Resistant Hypertension (RHT)