Paired Associative Stimulation in Stroke
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“Paired Associative Stimulation in Stroke”
Stroke is the third most common cause of death in the United States after heart disease and cancer, and the leading cause of long-term disability. This work will develop an innovative brain stimulation method (paired associative stimulation) which might set the stage for a new treatment for stroke rehabilitation.
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Device - Transcranial magnetic stimulation & median nerve stimulation
Paired associative stimulation (PAS) is a new technique where one pairs a peripheral stimulation with centrally applied transcranial magnetic stimulation (TMS), and produces plasticity, as measured by TMS MEP's. Currently PAS is performed with median nerve stimulation. PA25: The interval between median nerve stimulation and TMS was chosen to be 25 ms, which is called PAS25. 240 paired TMS and median nerve stimulation at a frequency of 0.2 Hz over 20 min. PAS10: 240 paired TMS and median nerve st ...read more on ClinicalTrials.org
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Paired Associative Stimulation Modulates Motor Excitability and Plasticity in Chronic Stroke Patients
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NCT02586597
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