common.study.topics.clinical

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

common.study.values.description

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

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Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Active delta-9-THC

Low dose (0.015 mg/kg = 1.05 mg in a 70 kg individual) THC, dissolved in alcohol. This dose is roughly equivalent to smoking approximately 1/4 of a marijuana cigarette, or "joint". Administered over 20 minutes.

Drug - Placebo

Control: small amount of alcohol (quarter teaspoon), with no THC. Administered over 20 minutes.

Drug - Active Ethanol

Target BrAC of 0.04% reached over 20 minutes and then clamped to maintain this dose for an additional 60 minutes. This dose is equivalent to consuming approximately 2 drinks over 1 hour. Administered over a total of 80 minutes.

Drug - Placebo

Control: no alcohol, administered for a total of 80 minutes.

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Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

common.study.values.clinical-trial-id

NCT02404688

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DbDwAa