common.study.topics.clinical

Methods for Stabilization in Opioid Dependence

common.study.values.description

Buprenorphine as Adjunct to Outpatient Induction Onto Vivitrol

The study will enroll 30 opioid-dependent participants into an open-label pilot outpatient study of methods to facilitate induction and stabilization onto XR-NTX. There will be three different methods of XR-NTX induction using increasing doses of oral naltrexone and buprenophine.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Buprenorphine

Buprenorphine will be administered daily

Drug - Naltrexone

On study day 2, participants will receive increasing doses of oral naltrexone prior to administration of XR-NTX

Drug - Vivitrol

Participants will receive one 380 i.m. injection on Study day 5 or 10, and another injection 4 weeks later.

participant.views.study.view.additional

participant.views.study.view.scientific-title

Buprenorphine as Adjunct to Outpatient Induction Onto Vivitrol

common.study.values.clinical-trial-id

NCT03113409

participant.views.study.view.id

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