common.study.topics.clinical

Menopausal Sleep Fragmentation and Body Fat Gain

common.study.values.description

Menopausal Sleep Fragmentation and Body Fat Gain

This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin response as a metabolic biomarker for body fat gain.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

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Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Leuprolide Acetate

one injection of open-label intramuscular dose of leuprolide (3.75-mg depot), a gonadotropin-releasing hormone agonist that rapidly suppresses estradiol and temporarily achieves ovarian suppression.

Fragmented sleep

Fragmented sleep will be experimentally induced.

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participant.views.study.view.scientific-title

Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in Women

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NCT03047330

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