Menopausal Sleep Fragmentation and Body Fat Gain
common.study.values.description
“Menopausal Sleep Fragmentation and Body Fat Gain”
This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin response as a metabolic biomarker for body fat gain.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
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common.study.methods.is-healthy-no
Drug - Leuprolide Acetate
one injection of open-label intramuscular dose of leuprolide (3.75-mg depot), a gonadotropin-releasing hormone agonist that rapidly suppresses estradiol and temporarily achieves ovarian suppression.
Fragmented sleep
Fragmented sleep will be experimentally induced.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in Women
common.study.values.clinical-trial-id
NCT03047330
participant.views.study.view.id
DdwvMb
