common.study.topics.clinical

Diagnosis of Acid Reflux Disease Using Novel Imaging

common.study.values.description

Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study

Gastroesophageal reflux disease (GERD), a common chronic disorder in the veteran population, is associated with drug costs exceeding $ 10 billion/year. Only 30-40% of patients with reflux symptoms have erosive esophagitis. The vast majority suffers from non erosive reflux disease (NERD), a condition in which standard endoscopy fails to identify any mucosal breaks and is unable to confirm the diagnosis. Unfortunately, a gold standard for the diagnosis of NERD does not exist. Narrow band imaging (NBI) utilizes spectral narrow band filters (incorporated into standard endoscopes) and helps to see abnormal areas not identified during standard endoscopy. Preliminary results have shown that NBI endoscopy may represent a significant improvement over standard endoscopy for the diagnosis of NERD. The purpose of this study is to accurately diagnosis non acid reflux disease by using a blue light (also known as NBI)upper endoscopy technique.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Esomeprazole

standard dose of proton pump inhibitor by mouth once a day for 30 days

Drug - Placebo

placebo

participant.views.study.view.additional

participant.views.study.view.scientific-title

Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study

common.study.values.clinical-trial-id

NCT02081404

participant.views.study.view.id

PdR10b