Alcohol Use Disorder and Post Traumatic Stress Disorder
common.study.values.description
“Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)”
This is a randomized controlled Phase II clinical trial designed to evaluate the effects of N-acetylcysteine (NAC) in reducing Alcohol Use Disorder (AUD) severity and Post Traumatic Stress Disorder (PTSD) symptomatology among individuals with current AUD and PTSD.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - N-Acetylcysteine (NAC) Treatment
Participant will receive 12 weeks of Active Treatment NAC (2400 mg) daily. The study medication will be provided in blister packs in the form of 600 mg tablets. Each participant will be asked to take two (2) 600 mg tablets in the morning and two (2) 600 mg tablets in the evening.
Behavioral - Cognitive Behavioral Therapy
Participant will receive 12 weeks of weekly cognitive-behavioral therapy, medication management, and AE monitoring.
Drug - Placebo Oral Capsule
Participant will receive 12 weeks of inactive placebo. The study medication will be provided in blister packs in the form of 600 mg tablets. Each participant will be asked to take two (2) 600 mg tablets in the morning and two (2) 600 mg tablets in the evening.
participant.views.study.view.additional
participant.views.study.view.scientific-title
A Randomized Controlled Trial of N-Acetylcysteine for Alcohol Use Disorder and Comorbid Post Traumatic Stress Disorder
common.study.values.clinical-trial-id
NCT02966873
participant.views.study.view.id
PdyDEb
