common.study.topics.clinical

Varenicline OTC Trial on Efficacy and Safety

common.study.values.description

Varenicline OTC Trial on Efficacy and Safety

The primary goal of the proposed research is to test whether varenicline (Chantix) is safe and effective as an over-the-counter (OTC) medication.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - 1.0mg Varenicline b.i.d.

Varenicline is classified as a selective nicotine receptor partial agonist (SNRPA) that works both to stimulate the nicotine receptor and block smoking reward at the α4β2 nicotinic receptor subtype.

Drug - 0.5mg Varenicline b.i.d.

Varenicline is classified as a selective nicotine receptor partial agonist (SNRPA) that works both to stimulate the nicotine receptor and block smoking reward at the α4β2 nicotinic receptor subtype.

Drug - 0.0mg placebo Varenicline b.i.d.

Product that looks like active varenicline, but contains no active ingredient

participant.views.study.view.additional

participant.views.study.view.scientific-title

Varenicline OTC Trial on Efficacy and Safety

common.study.values.clinical-trial-id

NCT03557294

participant.views.study.view.id

PdyQnd