common.study.topics.clinical

Impact of Escitalopram on Sperm DNA Fragmentation

common.study.values.description

“Impact of Escitalopram on Sperm DNA Fragmentation”

Double-blind placebo-controlled randomized trial of daily escitalopram for 6 weeks in healthy men with normal semen analyses and no psychiatric history of depression, bipolar, mania or suicidal ideation. Hormone profiles, semen analysis, sperm DNA fragmentation, and sexual function will be measured at baseline, after 6 weeks of therapy, and 4 weeks after discontinuation of therapy (10 weeks into study).

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Escitalopram

10mg by mouth daily for 6 weeks

Placebo

matched placebo control by mouth for 6 weeks

participant.views.study.view.additional

participant.views.study.view.scientific-title

Assessing the Impact of Escitalopram on Sperm DNA Fragmentation: A Randomized Placebo Controlled

common.study.values.clinical-trial-id

NCT03527043

participant.views.study.view.id

QbY4Aa