Influenza Vaccination in Patients Undergoing Cardiac Surgery

Eligibility Details: Inclusion Criteria: - Subjects who the investigator believes can and will comply with the requirements of the protocol (i.e. return for follow-up visits, and able to converse with study personnel) - Age 18 years or older - Undergoing major cardiac surgery using cardiopulmonary bypass Exclusion Criteria: - Have not received influenza vaccination in the past or cannot be vaccinated due to previous severe reaction to influenza vaccine, egg, latex, or thimerosol allergies, or refusal of vaccination - Participant has received a community available influenza vaccine within <6 months - History of Guillain-Barré syndrome - Immunosuppressive disorders or medications (including oral prednisone >10 mg daily, recent chemotherapy treatment) - Emergency cases as determined by the investigator or physician