Glucagon-Like Peptide-2 Mediated Secretion of Enteral Lipids

Glucagon-like Peptide-2 Mediated Secretion of Stored Enteral Lipids

Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) releases the triglyceride from the gut is not known. The research team in this study is interested in finding out how teduglutide (a degradation resistant form of GLP-2) releases stored triglyceride from the gut by studying samples from patients undergoing endoscopy and small bowel biopsy.

Pharmaceutical medication involved
Recruiting patients only

Drug - Teduglutide


Drug - Placebo


Investigating the Release of Stored Enteral Lipids in Response to a Single Subcutaneous Dose of Analogue Glucagon-like Peptide-2 in Humans