Functional Hypothalamic Activation in Response to Diazoxide
common.study.values.description
“Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide”
The goal of this study is to determine whether metabolic control centers in the brain can be activated in patients with type 2 diabetes as compared to non-diabetic individuals. This is important since people with diabetes have inappropriately high production of glucose, which could be at least in part due to impaired activation of important brain centers.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Diazoxide
Healthy and T2D participants will receive diazoxide at a dose of 4-7 mg/kg (based upon weight) between baseline MRI scan and second MRI scan.
Drug - Placebo
Healthy and T2D participants will receive placebo between baseline MRI scan and second MRI scan.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide
common.study.values.clinical-trial-id
NCT03566511
participant.views.study.view.id
QeZq5d
