Periodontal Phenotype Study (Tooth Extraction)

Periodontal Phenotype Study (Tooth Extraction)

The purpose of this trial is to determine the correlations between various tissue dimensions and the changes that occur following a single-tooth dental extraction in human adults. 65 adult subjects who are in need of dental extractions will be recruited. Clinical measurements will be gathered prior to and immediately following the single tooth extraction. There will be a 2-week post-operative visit to assess healing and a 14-week follow-up for photographic documentation and clinical measurements of the extraction area.

No pharmaceutical medication involved
Patients and healthy individuals accepted


At the initial screening examination, each subject will receive an informed consent form. Prior to signing the informed consent, one of the investigators or qualified staff will thoroughly discuss participation in the study with each subject, allocating time for questions and answers.


At the initial screening examination, complete medical and dental history will be obtained to verify eligibility.


each subject will undergo site-specific oral radiographic exam (new periapical radiographs will be obtained if needed) to evaluate potential study sites.

PVS Impressions

PVS impressions of the arch of interest will be obtained in order perform volumetric analysis of the area of interest.


Intraoral photographs will also be taken and subsequent study visits will be planned.


The patient will then be sent to the Department of Radiology at the College of Dentistry for a baseline CBCT and follow-up at 14 week CBCT. These CBCT's will be utilized to evaluate the hard tissue volume in comparison to the clinical volume of soft tissue.


After appropriate local anesthetic is administered and anesthesia is achieved, the buccal tissue thickness will be measured and recorded.

Procedure - Extraction

After the pre-extraction baseline measurements are recorded and adequate anesthesia is confirmed, minimally invasive extraction procedures will be initiated. All extractions will be performed by residents in the UI CoD Periodontics advanced education program.

Clinical measurements

Measuring soft tissue dimensions, bone thickness prior to and immediately after extraction and then after appropriate healing time frames.

Periodontal Phenotype and Supracrestal Soft Tissue Dimentions - Clinical Correlations and Their Impact on Post-extraction Volumetric Changes