common.study.topics.clinical

Treatment of Prostate Cancer

common.study.values.description

A Study of Rucaparib Versus Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib versus treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Recruiting patients only common.study.methods.is-healthy-yes

Drug - Rucaparib

Rucaparib will be administered daily.

Drug - Abiraterone acetate or Enzalutamide or Docetaxel

Abiraterone acetate and enzalutamide will be administered daily. Docetaxel will be administered every 3 weeks.

participant.views.study.view.additional

participant.views.study.view.scientific-title

TRITON3: A Multicenter, Randomized, Open Label Phase 3 Study of Rucaparib Versus Physician's Choice of Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Associated With Homologous Recombination Deficiency

common.study.values.clinical-trial-id

NCT02975934

participant.views.study.view.id

RdG2Lb