common.study.topics.clinical

Predictors of Outcomes in Psychiatric Disorders

common.study.values.description

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

In this study the investigators will seek to improve our understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of mood, substance use, and eating behavior. The investigators will recruit 1000 individuals and use a wide range of assessment tools, neuroimaging measures, blood and microbiome collections and behavioral tasks to complete the baseline and follow-up study visits. Upon completion, the investigators aim to have robust and reliable dimensional measures that quantify these systems and a set of assessments that should be recommended as a clinical tool to enhance outcome prediction for the clinician and assist in determining who will likely benefit from what type of intervention.

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common.study.values.methods

No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Behavioral - standardized diagnostic assessment

Behavioral - self-report questionnaires

Behavioral - behavioral tasks

physiological measurements

structural and functional magnetic resonance imaging and EEG

biomarker and microbiome assessments

blood to derive induced pluripotent stem cells

genetic and epigenetic assessments

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T-1000: Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

common.study.values.clinical-trial-id

NCT02450240

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Xe0XVe