MRI Imaging Effects of Cannabis Smoking
common.study.values.description
“Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking”
This is a longitudinal study of the long-term health impact of cannabis smoking on the lungs. Participants will be followed over a period of 10 years, and impacts of cannabis smoking on the lungs will be measured with magnetic resonance imaging (MRI) using hyperpolarized xenon-129 gas, pulmonary function tests, exercise capacity, computed tomography images and questionnaires.
common.study.values.location
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common.study.values.methods
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Diagnostic Test - Cardiopulmonary exercise testing (CPET)
Participants <35 will perform cardiopulmonary exercise testing as a measure of exercise capacity
Diagnostic Test - Sputum analysis
Participants will provide a sputum sample that will be analysed for eosinophils
Diagnostic Test - Blood analysis
Participants will have their blood drawn and analysed for eosinophil count.
Diagnostic Test - Hyperpolarized Xenon-129 MRI of the lungs
Participants will be imaged using MRI using hyperpolarized xenon-129 gas as a contrast gas
Diagnostic Test - Computed Tomography (CT)
Participants will undergo a CT scan of the thoracic cavity
Diagnostic Test - Pulmonary Function Tests (PFTs)
Participants will have their lung function evaluated using PFTs
Diagnostic Test - Six Minute Walk Test (6MWT)
Participants >35 years of age will perform the six minute walk test as a measure of exercise capacity
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participant.views.study.view.scientific-title
Longitudinal Study of Xenon-129 MRI Imaging of Effects of Cannabis Smoking on Lung Structure and Function
common.study.values.clinical-trial-id
NCT03909477
participant.views.study.view.id
aAD7je
