common.study.topics.clinical

Beta Events and Sensory Perception

common.study.values.description

“Beta Events and Sensory Perception”

Low-frequency brain rhythms in the alpha (8-14Hz) and beta (15-29Hz) bands are strong predictors of perception and functional performance in a range of tasks, and are disrupted in several disease states. The purpose of this study is to investigate a direct causal relationship between low-frequency brain rhythms and sensory perception, and to optimize commonly used TMS paradigms to impact sensory processing and perception in a similar manner as endogenous rhythms. To do so, this study combines human magnetic resonance imaging (MRI), electroencephalography (EEG), non-invasive brain stimulation (transcranial magnetic stimulation; TMS), and biophysically principled computational neural modeling.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Device - Online active TMS

One single pulse or triple pulse train (3 pulses, 20ms inter-pulse interval) of TMS will be delivered per trial (at least 5 seconds apart) "online", or during the tactile detection task, at less than or equal to 80% active motor threshold.

Device - Online sham TMS

One single pulse or triple pulse train (3 pulses, 20ms inter-pulse interval) of sham TMS will be delivered per trial (at least 5 seconds apart) "online", or during the tactile detection task. A sham TMS coil will be used that looks, feels and sounds like experimental TMS, but is incapable of of delivering TMS pulses.

participant.views.study.view.additional

participant.views.study.view.scientific-title

The Causal Role of Neocortical Beta Events in Human Sensory Perception

common.study.values.clinical-trial-id

NCT04062318

participant.views.study.view.id

aADkPe