Influence of Obesity on Endogenous Oxalate Synthesis
Study Description
“Influence of Obesity on Endogenous Oxalate Synthesis”
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation. By the administration of a controlled low oxalate diet the investigators will estimate endogenous oxalate synthesis in both non-obese and obese non-kidney-stone forming adults. This study seeks to thusly increase the understanding of the relationships between obesity and endogenous oxalate synthesis to serve as a platform to develop novel therapies for stone prevention.
Location
Methods
No pharmaceutical medication involved
Patients and healthy individuals accepted
Dietary Supplement - controlled diet
Participants will consume a diet that is controlled in its daily contents of oxalate, calcium, vitamin C and sodium, and in its content of carbohydrate, fat, and protein. Participants will be asked not to take any dietary supplements (vitamins, calcium or other minerals, herbal supplements, nutritional aids), to exercise strenuously, or to consume food or drink that is not provided to them as part of the controlled diet.
Additional Information
Official Study Title
Influence of Obesity on Endogenous Oxalate Synthesis
Clinical Trial ID
NCT03704350
ParticipAid ID
aKrQRe
