Vasodilation in Young Adults
common.study.values.description
“Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults”
Previous research has identified adenosine triphosphate (ATP) as an important vasodilator that is released from red blood cells during exercise and exposure to hypoxic environments in adult humans. Further, older adults appear to have lower blood flow during both of these stressors and also have lower amounts of ATP released from their red blood cells. However, the contribution of ATP to vasodilation in response to exercise and hypoxia is currently unknown due to the lack of an effective ATP receptor antagonist. We aim to determine whether Vitamin B6 or its metabolite, Pyridoxal-5-Phosphate (PLP) is an effective ATP receptor antagonist.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Adenosine
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Drug - Vitamin B 6
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Drug - Pyridoxal 5'-Phosphate
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Drug - Adenosine Triphosphate
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Drug - Acetylcholine
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Drug - Sodium Nitroprusside
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Drug - Adenosine Diphosphate
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Drug - Adenosine Monophosphate
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Drug - Uridine Triphosphate
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participant.views.study.view.additional
participant.views.study.view.scientific-title
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
common.study.values.clinical-trial-id
NCT03738943
participant.views.study.view.id
aKrYne
