Brain Microglial Activation in Neuropsychiatric Syndromes
common.study.values.description
“Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach”
The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in patients with more neuropsychiatric symptoms. Inflammation in the brain will identified by using Positron Emission Tomography (PET) with the radiotracer [11C]PBR-28.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - PET with radiotracer [11C]PBR-28
[11C]PBR-28 will be injected into subjects' veins during PET scanning.
Affective challenge
Affective challenge is the induction of, for example, mood or affective pain.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach
common.study.values.clinical-trial-id
NCT03705715
participant.views.study.view.id
aOY8pd
