Testing Experimental Medication in Healthy Subjects
common.study.values.description
“A Study on the Impact of Rabeprazole-induced Elevated Stomach pH on APO-Dabigatran Exposure in Healthy Volunteers”
Open-label, crossover study recruiting 46 healthy male volunteers comparing the absorption of APO-dabigatran 150 mg per oral (PO) in the absence or presence of a proton pump inhibitor. Participants will serve as their own control when comparing dabigatran exposure in the absence or presence of the proton pump inhibitor, Rabeprazole 20 mg.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - RABEprazole 20 Mg Oral Delayed Release Tablet
Absorption of APO-Dabigatran measured with and without influence of rabeprazole
Drug - APO-Dabigatran 150mg
Absorption of APO-Dabigatran post single dose
participant.views.study.view.additional
participant.views.study.view.scientific-title
Impact of Rabeprazole-induced Elevated Gastric pH on APO-Dabigatran Exposure in Healthy Volunteers
common.study.values.clinical-trial-id
NCT04157881
participant.views.study.view.id
aQW4Yd
