Single Dose Truvada Study

Single Dose Truvada Study

This study examines tenofovir (TFV) drug concentrations in adults one day after taking a single dose of TruvadaAR - a pill used to prevent and treat HIV infection. The results of this study will be used to improve the (efficacy/accuracy) of a white coat adherence (WCA) detection test - a blood test that can be used to indicate medication adherence. Participants will receive one dose of TruvadaAR, and provide 2 total samples of blood.

Pharmaceutical medication involved
Patients and healthy individuals accepted

Drug - Tenofovir

pre- and post-dosing measurements of TFV and TFV-DP in plasma and PBMCs.

Single Observed Dose Administration of Truvada® to Establish Single Dose Pharmacokinetic Standards in Healthy Individuals