common.study.topics.clinical

Topical Acetaminophen for Itch Relief

common.study.values.description

Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects

Currently, topical antihistamines and corticosteroids are mainly used for itching relief. However, the over the counter antihistamines are not effective on all itch conditions. Acetaminophen is a popular and widely used OTC drug for pain relief. Although its mode of action is still unknown, recent studies have shown that acetaminophen indirectly activates cannabinoid CB1 receptors. Recent studies have shown that topical cannabinoid agonists are effective for itch relief, the efficacy of topical acetaminophen will be tested for non-histaminergic itch relief.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Acetaminophen

Topical acetaminophen gel

Drug - Carbomer 980

Topical vehicle gel

participant.views.study.view.additional

participant.views.study.view.scientific-title

Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects

common.study.values.clinical-trial-id

NCT03997851

participant.views.study.view.id

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