common.study.topics.clinical

Adiposity and Endothelin Receptor Function

common.study.values.description

Adiposity and Endothelin Receptor Function

Elevated levels of ET-1 have been implicated in cardiovascular disease and some forms of hypertension. Due to the strong, positive correlation between obesity and hypertension, the present study will explore the contribution of adiposity in ETB receptor function and aim to elucidate if ETB receptor dysfunction is a major contributor to hypertension in obesity.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Candesartan

7 days of Candesartan (16mg/day)

Drug - Placebo

7 days of Placebo

participant.views.study.view.additional

participant.views.study.view.scientific-title

Adiposity and Endothelin Receptor Function

common.study.values.clinical-trial-id

NCT03583866

participant.views.study.view.id

b4xxxb