Dyspnea Assessment in Hemodialysis Patients
common.study.values.description
“Dyspnea Assessment in Hemodialysis Patients”
Shortness of breath is very common among patients on dialysis for kidney failure; however, its causes are often not understood. This study will explore the lungs and the heart of these patients to determine the causes of shortness of breath. The amount of salt in the body tissues, which tends to accumulate in dialysis patients and can also cause shortness of breath, will also be measured. Machines that exploit magnetic resonance, ultrasound and x-rays to take images of the body interior will be employed; in addition, breathing tests, questionnaires and blood tests will also be used. 20 patients on dialysis will be recruited and have two visits: one at the beginning of the study and one year later to observe any changes in the lungs, heart and salt accumulation over time.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
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common.study.methods.is-healthy-yes
Diagnostic Test - Echocardiography
Transthoracic 2D Speckle-Tracking Echocardiography
Diagnostic Test - Fractional Exhaled Nitric Oxide
Fractional Exhaled Nitric Oxide testing
Diagnostic Test - Pulmonary Function Tests
Spirometry and Plethysmography
Diagnostic Test - Six-Minute Walk Test
Six-Minute Walk Test
Diagnostic Test - Blood Sampling
Blood testing for: standard-of-care, inflammatory biomarkers, uremic toxins
Diagnostic Test - Lung MRI
Proton Lung Magnetic Resonance Imaging
Diagnostic Test - Sodium MRI
Sodium Soft Tissue Magnetic Resonance Imaging
Diagnostic Test - Chest CT
High-resolution Quantitative Chest CT
Diagnostic Test - Dyspnea Questionnaires
Modified Medical Research Council; University of California, San Diego Shortness of Breath Questionnaire; Borg Scale
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participant.views.study.view.scientific-title
Multimodal Assessment of Dyspnea, Cardiopulmonary Structure and Function in Chronic Hemodialysis Patients
common.study.values.clinical-trial-id
NCT03773991
participant.views.study.view.id
b68z7e
