Experimental Autologous Blood Transfusion in Healthy Adults

S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion

The Purpose of the study is to test the hypothesis that administration of an S-nitrosylating (SNO) agent can improve tissue oxygenation during transfusion of packed red blood cells (RBCs).

Pharmaceutical medication involved
Patients and healthy individuals accepted

Drug - SNO

S-nitrosylating agent (SNO) Inhalation

Drug - Normal Saline

Normal Saline transfusion

Drug - Red Blood Cell

Blood transfusion (RBCs)

Phase 1 Study of S-Nitrosylation Therapy to Improve Tissue Oxygenation During Autologous Blood Transfusion in Healthy Volunteer