common.study.topics.clinical

Testing Experimental Medication in Healthy Subjects

common.study.values.description

“Trial of Indole-3-Carbinol and Silibinin”

This is a non-therapeutic, Phase 1 clinical trial to examine the safety, pharmacokinetic (PK) characteristics, and pharmacodynamics (PD) effect of indole-3-carbinol (I3C) and silibinin (Sil) in healthy subjects.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Indole-3-Carbinol

Cohorts 2, 3, & 4: 400 mg PO BID

Drug - Silibinin

Cohorts 1 & 4: 720mg

Drug - Silibin

Cohort 3: 360mg

participant.views.study.view.additional

participant.views.study.view.scientific-title

Trial of Indole-3-Carbinol & Silibinin

common.study.values.clinical-trial-id

NCT03687073

participant.views.study.view.id

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