Perioperative Lidocaine and Ketamine in Abdominal Surgery
common.study.values.description
“Perioperative Lidocaine and Ketamine in Abdominal Surgery”
The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Lidocaine and ketamine
Perioperative lidocaine and ketamine infusion (see below for dosages and timings)
Drug - Lidocaine
Perioperative lidocaine infusion (1.5 mg/kg bolus followed by an infusion of 2 mg/kg/hour based on actual body weight; the bolus and infusion will be started after anesthesia induction and before surgical incision, and continued until 1 hour after transfer from the operating room to the PACU)
Drug - Ketamine
Perioperative ketamine infusion (0.5 mg/kg bolus followed by an infusion of 0.3 mg/kg/hour based on actual body weight; the bolus and infusion will be started after anesthesia induction and before surgical incision, and continued until 1 hour after transfer from the operating room to the PACU)
Drug - Placebo
Perioperative placebo infusion (normal saline)
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participant.views.study.view.scientific-title
Lidocaine and Ketamine in Abdominal Surgery
common.study.values.clinical-trial-id
NCT04084548
participant.views.study.view.id
bW6Jva
