Restoring Molecular Circadian Rhythm
common.study.values.description
“Restoring Molecular Circadian Rhythm”
The goal is to address the mechanisms that account for alteration of circadian rhythms with age. As the blood of aged individuals can produce this alteration, the investigators propose to use such blood samples to "age" circadian rhythms in cultured cells. The investigators will verify aged blood-dependent alteration of rhythms and then conduct molecular screens to reverse this decline. If the investigators identify specific genes that can restore molecular circadian rhythm in vitro, the investigators will explore these in animal models (Drosophila, mouse).
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-no
common.study.methods.is-healthy-no
Observational study without intervention
Observational study without intervention
participant.views.study.view.additional
participant.views.study.view.scientific-title
Exploratory Pilot Study to Discover Genes That Restore the Molecular Circadian Rhythm
common.study.values.clinical-trial-id
NCT04086589
participant.views.study.view.id
bYELnb
