Pharmacokinetics of Oxytocin at Cesarean Delivery
common.study.values.description
“Pharmacokinetics of Oxytocin at Cesarean Delivery”
The primary objective is to obtain data to inform the design of a population pharmacokinetic study of oxytocin after administration at CD as per standard institutional practice.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - oxytocin
PK measurements of oxytocin
Device - Shore durometer
The investigators will take serial readings from a digital durometer at the uterine fundus at 3, 6, 9 and 12 minutes following OXT administration to provide data that will inform an estimate of the timing of peak effect. Shore durometers measure the hardness of materials on a scale of 0-100 Shore Units (SU). Preliminary (unpublished) data provided a range of 10-56 SU after oxytocin administration at cesarean delivery. Durometer readings were also shown to correlate positively with the obstetrici ...read more on ClinicalTrials.org
participant.views.study.view.additional
participant.views.study.view.scientific-title
The Pharmacokinetics of Oxytocin in Pregnant Women Undergoing Cesarean Delivery - a Feasibility Pilot Study
common.study.values.clinical-trial-id
NCT03898882
participant.views.study.view.id
bkRVKa
