Dotarem Evaluation for Myocardial Perfusion CMR
common.study.values.description
“Dotarem Evaluation for Myocardial Perfusion CMR”
The overall goal of this study is to investigate the signal intensity and relaxation rate characteristics of gadoterate meglumine (Dotarem, Guerbet, USA) enhanced myocardium during rest and stress perfusion cardiovascular magnetic resonance (CMR) compared to gadobutrol (Gadavist) to prove that Dotarem provides constantly high myocardial relaxation necessary for accurate quantitative perfusion evaluation. The purpose of this study is to compare two types of contrast that patients receive during cardiac MRI scans to visualize the blood flow in the cardiac muscle. Both contrasts are used in standard of care procedures, and the one administered for each patient will be randomly selected. The length of the MRI study all procedures are the same as the clinically indicated scan.
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participant.ui.study.affiliations-map.online-study.header-virtual
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common.study.values.methods
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Drug - Gadavist 15Ml Solution for Injection
Group 2 (n=30) will receive the clinically approved gadobutrol (Gadavist, 0.1mmol/kg) as contrast agent. The contrast agents will be administered at a flow rate of 5.0 ml/s for both groups. In this study aim, all imaging protocols will comply with standard of care and only the perfusion data will be post-processed and analyzed.
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Dotarem Evaluation for Myocardial Perfusion CMR
common.study.values.clinical-trial-id
NCT03937921
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bo2PLa
