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Speech, Linguistic, Acoustic Markers in Parkinson's Disease

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Speech, Linguistic and Acoustic Markers in Parkinson's Disease

We aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. We will administer various speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls. We will also explore the associations between genetic factors and speech and cognitive status in Parkinson's disease.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Diagnostic Test - Cognitive Battery

Participants will be asked to complete a series of cognitive testing (testing of concentration, memory, and other thinking abilities).

Behavioral - Voice, Speech and Language Analysis

Participants will be asked to perform speaking and reading tasks, which will be recorded. Participants will be asked to complete a laptop-based test of language comprehension.

Behavioral - Questionnaires and Clinical Assessments

Participants with Parkinson's disease will complete an examination of their symptoms and questionnaires assessing disease symptoms, mood and activities of daily living. Healthy controls participants will be asked to complete questionnaires on mood.

Genetic - DNA Analysis

Participants will have their blood drawn for DNA analysis.

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Speech, Linguistic and Acoustic Markers in Parkinson's Disease

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NCT04273672

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dJ6J9d