Postpartum Low-Dose Aspirin and Preeclampsia
“Postpartum Low-Dose Aspirin and Preeclampsia”
The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia can persist postpartum. Women diagnosed with severe preeclampsia prior to delivery will be enrolled and randomized to receive either low-dose aspirin (81mg) or placebo to take daily for up to 3 weeks post-delivery.
Drug - Aspirin
Low dose aspirin, 81mg tablets, PO
Drug - Placebo oral capsule
Placebo oral capsule, PO
Low-Dose Aspirin in the Postpartum Period and Endothelial Function in Patients With Preeclampsia