common.study.topics.clinical

Effects of Psilocybin in Post-Traumatic Headache

common.study.values.description

Effects of Psilocybin in Post-Traumatic Headache

The purpose of this study is to investigate the effects of oral psilocybin in post-traumatic headache. Subjects will be randomized to receive placebo, low dose psilocybin, or high dose psilocybin on two separate test days approximately 14 days apart. Subjects will maintain a headache diary prior to, during, and after the treatments in order to document headache frequency and intensity, as well as associated symptoms. Blood samples will be drawn at various timepoints to measure levels of inflammatory peptides.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Placebo oral capsule

microcrystalline cellulose capsule

Drug - Low Dose Psilocybin

0.0143 mg/kg psilocybin capsule

Drug - High Dose Psilocybin

0.143 mg/kg psilocybin capsule

participant.views.study.view.additional

participant.views.study.view.scientific-title

Safety and Efficacy of Psilocybin for the Treatment of Headache Disorders: Sub-Study II

common.study.values.clinical-trial-id

NCT03806985

participant.views.study.view.id

dR6k0d