Fetal Genome Profiling via Trophoblast Cells
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“Fetal Genome Profiling Via Trophoblast Cells”
The objective of this study is to utilize trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for non-invasive prenatal testing. If we are able to validate that trophoblast cells obtained at an early gestational age can be reliably used for prenatal testing, there is great potential to improve early pregnancy management and counseling options for potential parents. The target population will be all women between the age of 18-45 undergoing care at the Center for Reproductive Medicine (CRM) in order to achieve a pregnancy.
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Diagnostic Test - Fetal Genome Profiling.
Once pregnancy is achieved, patients will undergo non-invasive collection of trophoblast cells (trophoblast retrieval and isolation from the cervix, TRIC) at an early gestational age, approximately 5-6 weeks. The patient will also be screened with blood work for carrier status for genetic conditions.
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Fetal Genome Profiling After Non-Invasive Isolation of Trophoblast Cells
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NCT03832634
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dwpgme
