common.study.topics.clinical

High Altitude and Exogenous Carbohydrate Oxidation

common.study.values.description

High Altitude and Exogenous Carbohydrate Oxidation

Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders. However, the mechanisms by which HA suppresses exogenous carbohydrate oxidation are not known. This study will seek to confirm that acute HA exposure decreases exogenous carbohydrate oxidation during steady-state aerobic exercise compared to SL, and explore if the mechanism inhibiting plasma glucose uptake is insulin dependent or independent.

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participant.ui.study.affiliations-map.online-study.header-virtual

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Sea Level

Carbohydrate consumed at 1.8 g/min during treadmill exercise at SL

High Altitude

Carbohydrate consumed at 1.8 g/min during treadmill exercise at HA

participant.views.study.view.additional

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The Mechanistic Effects of Acute Hypobaric Hypoxia on Exogenous Carbohydrate Utilization During Steady-state Aerobic Exercise

common.study.values.clinical-trial-id

NCT03851744

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