common.study.topics.clinical

Systematic Evaluation of Protamine Doze in Cardiac Surgery

common.study.values.description

Systematic Evaluation of Protamine Doze in Cardiac Surgery

The precise amount of protamine required to neutralize unfractionated heparin (UFH) remains unknown. This study will systematically identify the doze needed to neutralize UFH following cardiopulmonary bypass (CPB).

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Recruiting patients only common.study.methods.is-healthy-yes

Drug - Protamine Sulfate

Protamine Sulfate will be administered via an infusion pump to administer a 50 mg test doze, then 100 mg after 5 min waiting period. Following blood samples, additional alliquots of 50 mg will be measured to a maximum of 300 mg.

participant.views.study.view.additional

participant.views.study.view.scientific-title

Sysytematic Evaluation of Heparin and Protamine in Cardiac Surgery

common.study.values.clinical-trial-id

NCT03787641

participant.views.study.view.id

e31Orb