Neurocognitive Function Training in Older Adults

Strategic Training to Optimize Neurocognitive Functions in Older Adults

The goal of the present randomized control trial is to evaluate the efficacy of a novel cognitive training approach using simulated games, where older adults will learn to flexibly deploy attentional control during working memory, for prevention of Alzheimer's Disease (AD). Based on our extensive pilot work, we expect training-related enhancements in both neural and cognitive functions on a broad range of cognitive abilities due to the importance of attentional control and working memory in many types of cognition. These outcomes are widely applicable to the cognitive health and the quality of life of elderly Americans, and have further potential to offset degenerative processes common to normal aging.

No pharmaceutical medication involved
Patients and healthy individuals accepted

Behavioral - Low-C

This is the active control group, where participants will be trained to play an experimenter developed game that requires least attentional control among all arms.

Behavioral - High-C

In this intervention, participants will be trained on this experimenter developed game which requires a lot of attentional control.

Behavioral - High-C+

A commercial video game will be used that requires a lot of demand on attentional control.

Strategic Training to Optimize Neurocognitive Functions in Older Adults