“Pharmacokinetics of Neostigmine and Glycopyrrolate”
A group of 6 able-bodied healthy volunteers will receive Neostigmine (NEO) and Glycopyrrolate (GLY) intravenously and via 3 different methods of Iontophoresis (ION) with subsequent blood draws over 1 hour in order to measure the pharmacokinetic behavior of the drugs en-vivo.
Drug - Combination of Neostigmine and Glycopyrrolate
Intravenous or transdermal
Device - I-Box by Dynatronics
Electric field conducting drugs through the skin without compromising its integrity
Pharmacokinetics of Neostigmine and Glycopyrrolate After Intravenous and Transcutaneous Administration by Iontophoresis